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10.1021/tx500019u Chem

Neurology 96 , e2098e2108 (2021)

If youve been feeling drained, lightheaded, or struggling with focus, injections can provide relief faster than tablets

CFZ is highly lipophilic and is characterized by an unusually long pharmacokinetic half-life of up to 70 days, which is associated with extensive accumulation of the drug in the body [110,111,112]

Box: Hydroxocobalamin dosing schedule for the management of pernicious anaemia If no neurological involvement: Loading dose: 1,000 micrograms three times per week for two weeks Maintenance dose: 1,000 micrograms every two to three months If neurological involvement: Loading dose: 1,000 micrograms every other day until no further improvement Maintenance dose: 1,000 micrograms every two months Injections are usually administered at a GP surgery, although some patients can be taught to self administer[22]

Acosta Lopez MJ, Trevisson E, Canton M, Vazquez-Fonseca L, Morbidoniet V, et al